Health Canada Warns Cancer Drug Avastin Linked 2 Flesh-Eating Disease Cases

This article was last updated on April 16, 2022

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In a press statement released today by Health Canada, it was revealed that a cancer-treatment drug, Avastin, has been found responsible in two cases of flesh-eating disease, including one death. The warning was issued by the agency in combination and assistance of the drug’s manufacturer, Hoffmann-La Roche Ltd., after a previous warning by the U.S. Food and Drug Administration. However, the warning did not disclose any specific details into the two Canadian cases.

Avastin is a drug commonly used either to separately treat a particular type of brain cancer (glioblastoma) or in combination with chemotherapy to treat cancers that have spread to other parts of the body such as colon, rectal and lung cancer. In an official letter addressed by the company officials to health-care professionals posted on Health Canada’s website, it was mentioned that “Roche has conducted a comprehensive safety review that has identified 52 serious case reports of necrotizing fasciitis that occurred between November 1997 and September 2012, worldwide.” Furthermore, the letter also revealed that “two of these reports occurred in Canada. A total of 17 of the global cases reported a fatal outcome, including one Canadian death.”

Additionally, the agency explained that necrotizing fasciitis is a severe, fast-moving and life-threatening bacterial infection of the skin and soft tissue. There could be numerous reasons and conditions that could lead to the disease, which also threatened the life of former Quebec premier Lucien Bouchard in the early 1990s.

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